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Dr. James Berry advises parents whose children are using dangerous substances like opioids, heroin, fentanyl, methamphetamine, or cocaine to act immediately due to the high risk of overdose and death. He emphasizes the urgency of seeking professional help, starting with consulting a pediatrician to get advice and resources. Dr. Berry also suggests educating oneself through reading and contacting local behavioral health clinics for support and services. This is considered a life-threatening situation, and quick intervention is critical.